![]() ![]() ![]() With a lumbar puncture, physicians can look for abnormalities in the cerebrospinal fluid, which can be helpful when creating a differential diagnosis 2.Ĭerebrospinal fluid is made by tissue called the choroid plexus that lines the ventricles (hollow spaces) in the brain. Importantly, cerebrospinal fluid can be examined clinically through a lumbar puncture. Cerebrospinal fluid (CSF) is then reabsorbed directly into the blood through structures in the arachnoid mater called arachnoid villi (arachnoid granulations). After production, the cerebrospinal fluid travels through the ventricles and then around the brain and spinal cord. However, a smaller portion is produced by the ependymal cells which line the ventricles. Most this cerebrospinal fluid is produced in the ventricles of the brain by the choroid plexus. ![]() Depending on the rate of production and absorption (which varies person to person), the supply of cerebrospinal fluid can be replaced about every 7.5 hours. It should be noted that cerebrospinal fluid is continuously generated and reabsorbed. The brain produces about 500 mL of cerebrospinal fluid per day, but the cerebrospinal fluid is constantly reabsorbed at the same rate and only 100 to 160 mL is normally present at one time 1. Cerebrospinal fluid leak possible complications What is cerebrospinal fluidĬerebrospinal fluid (CSF) is a clear, colorless liquid that can be found around and within the ventricles and canals of the central nervous system (brain and spinal cord) and bathes its external surface. ![]()
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